Malaria Treatment Guidelines

Guidelines for the Treatment of Malaria in Malawi, 6th Edition, 2025. Ministry of Health, Malawi — National Malaria Control Programme.

1Severe Malaria

2.1Recognition & Diagnosis of Severe Malaria
2.2.1Pre-referral Treatment (Community & Health Centre)
2.2.2In-patient Management — the 8-8-8 Schedule
2.2.2.1Definitive Treatment — Parenteral Artesunate
2.2.2.2Definitive Treatment — Parenteral Quinine
2.3Post Discharge Malaria Continuum of Care (PDMCC)

2Uncomplicated Malaria

1.1Case Definitions & Diagnosis
1.3First-line Treatment — Multiple First-line Therapies (MFT)
1.4Treatment Failure
1.4.1Second-line Treatment — Artesunate-Amodiaquine (ASAQ)
1.5Learner Treatment Kit (LTK)

3Malaria in Pregnancy

3.1Intermittent Preventive Treatment (IPTp)
3.2Uncomplicated Malaria in Pregnancy
3.2.3Severe Malaria in Pregnancy
3.3Specific Messages for Pregnant Women

4Guide to Coma Scales

4.1Blantyre Coma Scale (children < 12 years)
4.2Glasgow Coma Scale (adults & children ≥ 12 years)

5Selective Antimalarial Chemoprophylaxis

5.1Risk Groups & Advice
5.3Prophylaxis Regimens

Guidelines for the Treatment of Malaria in Malawi, 6th Edition (January 2025), National Malaria Control Programme. Reproduction permission to be confirmed with the Secretary for Health.