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14.3

Non-standard (NS) ART regimens

Clinical HIV Guidelines, 5th Edition, 2022. Chapter 14, Understanding ART regimens and formulations.

Clinical description

  • Only expert ART clinicians can initiate NS regimens.
  • Patients with multiple contraindications and/or adverse reactions against all standard NRTIs (TDF,

AZT, ABC) or NNRTIs (EFV) may need a NS regimen.

  • Consider ATV/r or LPV/r for substitution of DTG, and EFV.
  • Contact the DHA for availability of non-standard ARVs (see section 26 on page 126).

o Provide patient history, indication and proposed regimen.

Check doses against the printed guideline and your clinical judgement before treating a patient. Spotted an error? Report it from the contact links below.

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