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14.1.6

Adverse events / side effects

Clinical HIV Guidelines, 5th Edition, 2022. Chapter 14, Understanding ART regimens and formulations.

Clinical description

  • Choose the appropriate alternative regimen for patients with:

o Contraindications o Moderate to severe side-effects (immediately)

o Troubling side effects that did not improve within 2 weeks with symptomatic treatment.

  • Use Alt. 2 if Alt. 1 can’t be used due to previous toxicity or other specific contraindications.
  • The appropriate 2nd line regimen depends on the 1st line regimen the patient was on when

confirmed with treatment failure. Only certified Level 2 ART providers can initiate 2nd line.

Check doses against the printed guideline and your clinical judgement before treating a patient. Spotted an error? Report it from the contact links below.

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