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9.7

Typhoid in Children

Malawi Standard Treatment Guidelines, 6th Edition, 2023. Chapter 9, Infectious Diseases.

Clinical Description

Bacterial disease caused by salmonella typhi and spread through contaminated food, water or close contact.

Signs and Symptoms

  • Fever, skin rash (rose spots)
  • Abdominal pain
  • Cough
  • Vomiting
  • Diarrhea or constipation

Investigations

  • Full blood count
  • Blood culture
  • Urea, electrolytes and creatinine
  • Erect abdominal Xray if suspect bowel perforation

Pharmacological

  • Ciprofloxacin 10mg/kg PO 12 hourly for 14 days. If not tolerating orals give

Ceftriaxone 50mg/kg IV 24 hourly. Change to ciprofloxacin once child can take orally to complete 14 days.

Non-pharmacological

  • Surgical referral if bowel perforation is suspected or GIT bleeding
  • Ensure good hand hygiene and proper stool disposal
  • Maintain good nutrition
  • Counsel guardians on good sanitation and hygiene

Complications

  • Bowel perforation
  • GIT bleeding
  • Psychosis

Complications and Referral Criteria

Suspected bowel perforation or GIT bleeding

Check doses against the printed guideline and your clinical judgement before treating a patient. Spotted an error? Report it from the contact links below.

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