9.7
Typhoid in Children
Malawi Standard Treatment Guidelines, 6th Edition, 2023. Chapter 9, Infectious Diseases.
Clinical Description
Bacterial disease caused by salmonella typhi and spread through contaminated food, water or close contact.
Signs and Symptoms
- Fever, skin rash (rose spots)
- Abdominal pain
- Cough
- Vomiting
- Diarrhea or constipation
Investigations
- Full blood count
- Blood culture
- Urea, electrolytes and creatinine
- Erect abdominal Xray if suspect bowel perforation
Pharmacological
- Ciprofloxacin 10mg/kg PO 12 hourly for 14 days. If not tolerating orals give
Ceftriaxone 50mg/kg IV 24 hourly. Change to ciprofloxacin once child can take orally to complete 14 days.
Non-pharmacological
- Surgical referral if bowel perforation is suspected or GIT bleeding
- Ensure good hand hygiene and proper stool disposal
- Maintain good nutrition
- Counsel guardians on good sanitation and hygiene
Complications
- Bowel perforation
- GIT bleeding
- Psychosis
Complications and Referral Criteria
Suspected bowel perforation or GIT bleeding
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