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9.1.2

Post Exposure Prophylaxis (PEP)

Malawi Standard Treatment Guidelines, 6th Edition, 2023. Chapter 9, Infectious Diseases.

Clinical Description

  • PEP involves giving ARV's following possible exposure to HIV to prevent infection.

PEP should be given as soon as possible and within 72hrs of high-risk exposure. For more information, refer to 2021 Clinical Management of HIV in Children and Adults (5th edition, 2021)

Weight Standard Alternative 3.0- 19.9kg 15PP: ABC 120mg / 3TC 60mg +DTG 10mg AZT 60mg / 3TC 30mg 24.9kg 15PA: ABC 120mg / 3TC 60mg + DTG 50mg

AZT 60mg / 3TC 30mg 29.9kg 15A: ABC 600mg / 3TC 300mg +DTG 50mg AZT 300mg / 3TC 150mg ≥ 30.0kg 13A: TDF 300mg / 3TC 300mg / DTG 50mg AZT 300mg / 3TC 150mg

Check doses against the printed guideline and your clinical judgement before treating a patient. Spotted an error? Report it from the contact links below.

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