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5.6.1

Mild Reaction

Malawi Standard Treatment Guidelines, 6th Edition, 2023. Chapter 5, Blood and Haematology.

Signs and Symptoms

  • Itchy rash

Possible cause: hypersensitivity (mild)

Treatment

  • Stop the transfusion
  • Administer antihistamine IM/IV or PO
  • Chlorpheniramine 0.1 mg/kg IM or IV for children; 10mg IM/IV for adult alternatively Chlorpheniramine 4mg PO or
  • Promethazine 6.25-12.5mg for children aged 5-12 yrs and 25mg for adults.
  • If no clinical improvement within 30 minutes or if signs and symptoms worsen, treat as Category 2.

Check doses against the printed guideline and your clinical judgement before treating a patient. Spotted an error? Report it from the contact links below.

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