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5.6

Adverse Reactions to Transfusion

Malawi Standard Treatment Guidelines, 6th Edition, 2023. Chapter 5, Blood and Haematology.

Clinical Description

  • Suspect an adverse reaction if any of the following occurs:
  • Severe pain at transfusion site or in the back, loin and/or chest
  • Rise in temperature of 1 Degree Celsius above the baseline
  • Increase in pulse rate of >20/minute above baseline
  • Fall in systolic BP >20 mm Hg
  • Urticaria
  • Rigors
  • Hemoglobinuria
  • Shortness of breath
  • Wheezing
  • Treatment depends on the severity of the transfusion reactions.

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