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17.1.4

PID: In-Patient Treatment

Malawi Standard Treatment Guidelines, 6th Edition, 2023. Chapter 17, Sexually Transmitted Infections.

Clinical Description

  • A triad of lower abdominal pain, abnormal vital signs (particularly fever and tachycardia) and peritonism (guarding or rebound tenderness with cervical motion and adnexal tenderness).
  • Patients additionally have positive risk screen and abnormal vaginal discharge

Signs and Symptoms

  • Failure to respond to syndromic treatment regime within 72 hours
  • Presence of tender pelvic mass which may be an abscess or an ectopic pregnancy
  • History or suspicion of recent induced abortion, delivery, or miscarriage
  • Active vaginal bleeding
  • Missed, overdue or delayed period

Pregnancy

  • Heavy menstrual bleeding
  • Vomiting

Note: The patient should be admitted

Pharmacological

If deranged vital signs, dehydration etc.

  • Give IV fluids
  • Offer analgesia
  • Parenteral antibiotics.

1st line Ceftriaxone 2g IV 24 hourly metronidazole 500mg IV 8 hourly alternative 1st line Gentamicin 240mg IV 24 hourly

Metronidazole 500mg IV 8 hourly

Ampicillin 1g IV 8 hourly

  • When improved and able to swallow switch to oral antibiotics:
  • Doxycycline 100mg 12 hourly and
  • Metronidazole 400mg 8 hourly for 10 days
  • Analgesic
  • If pain is severe:
  • Give Pethidine 100 mg IM then PRN

Notes:

  • Post abortal sepsis and puerperal sepsis may present as acute PID. If these are recognized, the following must be done:
  • Admit and treat with parenteral antibiotic therapy.
  • If retained products of conception suspected, evacuate the uterus within 12 hours of antibiotic therapy regardless of the patient's temperature
  • Provide supportive care such as blood transfusion, iv fluids and closely monitor vital signs.

Check doses against the printed guideline and your clinical judgement before treating a patient. Spotted an error? Report it from the contact links below.

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