17.1.4
PID: In-Patient Treatment
Malawi Standard Treatment Guidelines, 6th Edition, 2023. Chapter 17, Sexually Transmitted Infections.
Clinical Description
- A triad of lower abdominal pain, abnormal vital signs (particularly fever and tachycardia) and peritonism (guarding or rebound tenderness with cervical motion and adnexal tenderness).
- Patients additionally have positive risk screen and abnormal vaginal discharge
Signs and Symptoms
- Failure to respond to syndromic treatment regime within 72 hours
- Presence of tender pelvic mass which may be an abscess or an ectopic pregnancy
- History or suspicion of recent induced abortion, delivery, or miscarriage
- Active vaginal bleeding
- Missed, overdue or delayed period
Pregnancy
- Heavy menstrual bleeding
- Vomiting
Note: The patient should be admitted
Pharmacological
If deranged vital signs, dehydration etc.
- Give IV fluids
- Offer analgesia
- Parenteral antibiotics.
1st line Ceftriaxone 2g IV 24 hourly metronidazole 500mg IV 8 hourly alternative 1st line Gentamicin 240mg IV 24 hourly
Metronidazole 500mg IV 8 hourly
Ampicillin 1g IV 8 hourly
- When improved and able to swallow switch to oral antibiotics:
- Doxycycline 100mg 12 hourly and
- Metronidazole 400mg 8 hourly for 10 days
- Analgesic
- If pain is severe:
- Give Pethidine 100 mg IM then PRN
Notes:
- Post abortal sepsis and puerperal sepsis may present as acute PID. If these are recognized, the following must be done:
- Admit and treat with parenteral antibiotic therapy.
- If retained products of conception suspected, evacuate the uterus within 12 hours of antibiotic therapy regardless of the patient's temperature
- Provide supportive care such as blood transfusion, iv fluids and closely monitor vital signs.
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