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7.11

Peritonitis

Malawi Standard Treatment Guidelines, 6th Edition, 2023. Chapter 7, Gastrointestinal Conditions.

Clinical Description

  • Refers to inflammation of the peritoneum.
  • Possible Causes: appendicitis, pancreatitis, acute cholecystitis, bowel obstruction or perforated peptic ulcer.

Signs and Symptoms

  • Rebound tenderness, guarding, rigidity of the abdominal wall. The patients may also present in septic shock if there is a bowel perforation, appendiceal rupture or cholangitis.

Investigations

  • Full blood count
  • Group and save
  • Amylase and lipase (if pancreatitis suspected)
  • Abdominal x-ray (supine and erect) if obstructive causes suspected
  • Abdominal ultrasound – if pancreatitis, appendicitis, cholecystitis suspected

Treatment

  • Intravenous fluids, analgesia, NPO and insert nasogastric tube
  • IV antibiotics: Only indicated for appendicitis, cholecystitis and bowel obstruction with perforation.
  • Do not prescribe antibiotics for pancreatitis or bowel obstruction without perforation.
  • IV Ceftriaxone 2g 24 hourly for 5-7 days
  • IV Metronidazole 500mg 8 hourly for 5 – 7 days

Surgery:

  • Indicated in all patients with peritonitis, large bowel obstruction, adhesions and small bowel obstruction after failed conservative management, appendicitis (with or without rupture) and perforated peptic ulcers.
  • Indicated for all bowel obstruction due to adhesions or other causes if full blood count shows a leucocytosis.

Complications and Referral Criteria

  • if there is no expertise available.
  • If the patient is operated and develops complications and requires ICU or re – operation.
  • For cholecystitis if no improvement after course of antibiotics.

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