7.11
Peritonitis
Malawi Standard Treatment Guidelines, 6th Edition, 2023. Chapter 7, Gastrointestinal Conditions.
Clinical Description
- Refers to inflammation of the peritoneum.
- Possible Causes: appendicitis, pancreatitis, acute cholecystitis, bowel obstruction or perforated peptic ulcer.
Signs and Symptoms
- Rebound tenderness, guarding, rigidity of the abdominal wall. The patients may also present in septic shock if there is a bowel perforation, appendiceal rupture or cholangitis.
Investigations
- Full blood count
- Group and save
- Amylase and lipase (if pancreatitis suspected)
- Abdominal x-ray (supine and erect) if obstructive causes suspected
- Abdominal ultrasound – if pancreatitis, appendicitis, cholecystitis suspected
Treatment
- Intravenous fluids, analgesia, NPO and insert nasogastric tube
- IV antibiotics: Only indicated for appendicitis, cholecystitis and bowel obstruction with perforation.
- Do not prescribe antibiotics for pancreatitis or bowel obstruction without perforation.
- IV Ceftriaxone 2g 24 hourly for 5-7 days
- IV Metronidazole 500mg 8 hourly for 5 – 7 days
Surgery:
- Indicated in all patients with peritonitis, large bowel obstruction, adhesions and small bowel obstruction after failed conservative management, appendicitis (with or without rupture) and perforated peptic ulcers.
- Indicated for all bowel obstruction due to adhesions or other causes if full blood count shows a leucocytosis.
Complications and Referral Criteria
- if there is no expertise available.
- If the patient is operated and develops complications and requires ICU or re – operation.
- For cholecystitis if no improvement after course of antibiotics.
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