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7.1

Amoebiasis

Malawi Standard Treatment Guidelines, 6th Edition, 2023. Chapter 7, Gastrointestinal Conditions.

Clinical Description

An infection caused by protozoan Entamoeba histolytica transmitted through food and drink contaminated with human faeces.

  • Clinical manifestations
  • Intestinal: amoebic dysentery
  • Hepatic: amoebic liver abscess

Signs and Symptoms

  • Diarrhoea (dysentery) +/- fever
  • Abdominal pain
  • Right upper quadrant abdominal pain and jaundice in amoebic liver abscess

Investigations

  • Full blood count
  • Fresh wet stool analysis
  • Liver function test
  • Abdominal Ultrasound (if amoebic liver abscess suspected)

Non-pharmacological

  • Health education on fecal disposal, hand washing and food hygiene.

Pharmacological

Intestinal Amoebiasis

Adults

  • Metronidazole 800mg 8 hourly for 5 days’ preferably after food.

Children

  • Metronidazole 7.5 mg/kg 8 hourly for 5 days

Check doses against the printed guideline and your clinical judgement before treating a patient. Spotted an error? Report it from the contact links below.

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