8.2.2
Cryptococcocaemia
Clinical HIV Guidelines, 5th Edition, 2022. Chapter 8, HIV-related diseases.
Signs and symptoms
Often no clinical signs. Note: the lack of meningitis signs does not rule out active CM.
Investigations
Serum CrAg test positive but CSF is negative for CrAg and/or microscopy (Indian ink).
Assess for meningitis signs. If positive, do full investigation and treatment for active CM (see section 8.2.1
Treatment
Fluconazole tablets 800 mg 24-hourly for 2 weeks, then 400 mg 24-hourly for 8 weeks, then 200mg 24-hourly for life
Check doses against the printed guideline and your clinical judgement before treating a patient. Spotted an error? Report it from the contact links below.
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