4.2.9
Disadvantages of LPA
National TB Management Guidelines, 2018 Edition. Chapter 4, Approach to TB diagnosis.
Clinical description
- Requires well-trained staff;
- Requires at least three rooms for the different steps;
- Can only be performed on bacillary isolates from smear or culture;
- Infection control precautions require sophisticated biosafety level (BSL-3).
- Prone to contamination
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