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4.1

Clinical presentation

National TB Management Guidelines, 2018 Edition. Chapter 4, Approach to TB diagnosis.

Clinical description

Active TB disease causes a variety of symptoms depending on the anatomical site(s) involved. In high HIV prevalence settings such as Malawi, patients may present with symptoms suggestive of extra-pulmonary disease or both pulmonary and extra-pulmonary disease.

  • Patients should be highly suspected of TB and undergo a thorough investigation for

TB if:

o They are children who have been in close contact with a known TB patient;

o They are HIV positive; or o They were previously treated for TB.

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