Skip to content
Malawi Clinical GuidelinesGuidelinesGet app

5.1

LAP — Key Facts & Diagnosis

Guidelines for Management of Sexually Transmitted Infections, 5th Edition, 2025. Chapter 5, Lower Abdominal Pain in Women (LAP).

Figure from the guideline
Figure, page 35 of the printed guideline. Open the image to zoom.

Clinical description

  • Main symptoms: lower abdominal/pelvic pain, often bilateral. ± vaginal discharge, irregular menstrual bleeding, dyspareunia, dysuria, fever/chills.
  • Wide range of causes: PID (STI and non-STI), gynaecological/obstetric (ectopic pregnancy, abortion, ovarian cyst), surgical (appendicitis, diverticulitis), UTI, gastroenteritis.
  • Danger signs: missed period (ectopic?), recent delivery/abortion/miscarriage, fever >38 °C, palpable mass, heavy bleeding. → urgent OB-GYN/surgical referral.
  • Syndromic PID treatment covers all common STI and non-STI causes given the potential severity and difficulty identifying the underlying cause.

Treatment

With abdominal tenderness / cervical excitation / vaginal discharge

  • Ceftriaxone 500 mg IM stat.
  • Azithromycin 1000 mg oral stat.
  • Metronidazole 400 mg oral BD for 14 days.
  • Doxycycline 100 mg oral BD for 14 days. (Avoid in PBFW and children.)

Mild/no abdominal tenderness

  • Metronidazole 400 mg oral BD for 5 days.
  • If thick/cream discharge, burning/swelling: add clotrimazole 500 mg vaginal pessary stat.

Always give a 3-day review appointment. If not improved: speculum exam for cervicitis, refer for labs (NG, CT, TV), add praziquantel 40 mg/kg oral stat, ensure partner treatment.

Partner treatment

Partner treatment (asymptomatic)

  • Ceftriaxone 500 mg IM stat + azithromycin 1000 mg oral stat + doxycycline 100 mg oral BD for 14 days.

At every visit

HIV & ART status

  • Ascertain HIV + ART status from health passport or self-report.
  • Offer new HIV test for all unless previously diagnosed. Do not use coercion.
  • New positive: active referral for ART initiation.
  • New negative: refer/offer PrEP, VMMC, consistent condom use.
  • Known positive: reinforce ART adherence or refer for re-initiation.

Hepatitis B

  • Offer HBV rapid test for all patients born before 2002.
  • HBsAg negative: refer for HBV vaccination unless previously completed 3 doses.
  • HBsAg positive: refer for clinical and treatment assessment.

Syphilis screening

  • Offer syphilis rapid test for concurrent asymptomatic syphilis (except in GUD/ARI where it does not influence treatment decisions).

Risk reduction & condoms

  • Risk reduction counselling. Promote and dispense condoms.
  • Promote VMMC for all non-circumcised men. Schedule appointment in 2 weeks.

Tables and figures

Figure from the guideline
Table, page 36 of the printed guideline. Open the image to zoom.

Check doses against the printed guideline and your clinical judgement before treating a patient. Spotted an error? Report it from the contact links below.

Need this without data?

The app holds every guideline on your device, with calculators, bookmarks and notes.