23.4
Pellagra (vitamin B3/NIACIN Deficiency)
Malawi Standard Treatment Guidelines, 6th Edition, 2023. Chapter 23, Nutritional Disorders.
Clinical Description
Nicotinic acid deficiency, a condition known as pellagra is usually accompanied by other
Vitamin deficiencies.
CLINICAL FEATURES AND DIAGNOSIS
Include the triad of diarrhea, dementia and dermatitis (darkening of sun-exposed skin)
Treatment
Objectives
- To prevent complications associated with the deficiency
- To replenish the deficient Vitamin B3
- Children: Nicotinamide, oral, 50mg 8 hourly for 2 weeks.
- Adults: Nicotinamide, oral, 100mg 8 hourly for 2 weeks.
- For Malnutrition clients, refer to inpatient care CMAM/NCST guidelines
Dietary advice
- Increase intake of liver, kidneys, other meats, poultry and fish, peanuts, milk, pulses, whole meal wheat and bran, Reduce intake of alcohol.
- Encourage diversification (6 food groups)
Complications and Referral Criteria
- Refer all clients that have failed to respond to the above treatment
- Vitamin A Deficiency (Xerophthalmia)
Check doses against the printed guideline and your clinical judgement before treating a patient. Spotted an error? Report it from the contact links below.
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