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23.4

Pellagra (vitamin B3/NIACIN Deficiency)

Malawi Standard Treatment Guidelines, 6th Edition, 2023. Chapter 23, Nutritional Disorders.

Clinical Description

Nicotinic acid deficiency, a condition known as pellagra is usually accompanied by other

Vitamin deficiencies.

CLINICAL FEATURES AND DIAGNOSIS

Include the triad of diarrhea, dementia and dermatitis (darkening of sun-exposed skin)

Treatment

Objectives

  • To prevent complications associated with the deficiency
  • To replenish the deficient Vitamin B3
  • Children: Nicotinamide, oral, 50mg 8 hourly for 2 weeks.
  • Adults: Nicotinamide, oral, 100mg 8 hourly for 2 weeks.
  • For Malnutrition clients, refer to inpatient care CMAM/NCST guidelines

Dietary advice

  • Increase intake of liver, kidneys, other meats, poultry and fish, peanuts, milk, pulses, whole meal wheat and bran, Reduce intake of alcohol.
  • Encourage diversification (6 food groups)

Complications and Referral Criteria

  • Refer all clients that have failed to respond to the above treatment
  • Vitamin A Deficiency (Xerophthalmia)

Check doses against the printed guideline and your clinical judgement before treating a patient. Spotted an error? Report it from the contact links below.

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