21.5
Use of Medicines in Renal DYSFUNCTION/IMPAIRMENT
Malawi Standard Treatment Guidelines, 6th Edition, 2023. Chapter 21, Renal Conditions.
Clinical Description
Note: Take great care when prescribing any medicine and carefully check medicine prescribing information (e.g. in BNF, MNF) regarding use in renal failure/impairment
Usually safe medicines:
- Doxycycline
- Erythromycin
- Penicillin
- Phenytoin
- Rifampicin
Use with care in reduceddoses:
- Amoxycillin
- Chloramphenicol (avoid in severe impairment)
- Cotrimoxazole
- Diazepam
- Digoxin
- Insulin
- Isoniazid-containing medicines
- Pethidine (increase dose interval, avoid in severe impairment)
- Phenobarbitone
- Propranolol
- Antiretroviral medicines
Avoid using:
- ACE inhibitors (eg. Captopri)
- Aspirin and other NSAIDS (eg. Ibuprofen, Indomethacin, diclofenac)
- Codeine
- Ethambutol
- Gentamycin
- Nalidixic acid
- Nitrofurantoin
- Streptomycin
Check doses against the printed guideline and your clinical judgement before treating a patient. Spotted an error? Report it from the contact links below.
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