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15.1.3

Intermittent Presumptive Treatment of Malaria in Pregnancy (IPTP)

Malawi Standard Treatment Guidelines, 6th Edition, 2023. Chapter 15, Parasitic Conditions.

Clinical Description

  • Intermittent Presumptive Treatment of malaria in pregnancy (IPTp) is one of the major malaria preventive strategies in Malawi
  • Pregnant women should receive at least three doses of Sulfadoxine-Pyrimethamine (SP) 525mg after the first trimester
  • Administer three tablets of SP with each scheduled antenatal care visit after 1st trimester (at 13 weeks’ gestation)
  • The doses should be administered at least four weeks apart and given as directly observed therapy (DOT)
  • The last dose of SP can be delivered safely up until the time of delivery
  • Sulfadoxine-Pyrimethamine can be given either on an empty stomach or with food

Note: HIV positive women receiving Cotrimoxazole Prophylaxis should not receive SP

Check doses against the printed guideline and your clinical judgement before treating a patient. Spotted an error? Report it from the contact links below.

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