24.1.2
When to suspect an ADR
Clinical HIV Guidelines, 5th Edition, 2022. Chapter 24, Pharmacovigilance.
Clinical description
- An ADR should be suspected when any of the following AE criteria are met:
a) Medicines with a known high risk for ADRs b) Medicines with narrow therapeutic index or potential for multiple interactions.
c) Sudden discontinuation of therapy or change of regimen d) Dose reduction indicated e) Prescription of ADR management medications: e.g., corticosteroids, adrenaline, vitamin K, dextrose 50%, antihistamines, etc.
f) In-patients with abnormal lab results g) Development of a new AE on long-term medication
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